中西药联合治疗溃疡性结肠炎35例疗效观察

Ulcerative Colitis Treated with Integration of TCM and Western Medicine:Effect Observation on 35 Cases

为观察中西药联合治疗溃疡性结肠炎的疗效,将70例溃疡性结肠炎患者随机分为对照组和观察组,每组35例。对照组患者给予甲基泼尼松龙等西药治疗,观察组患者在对照组治疗的基础上联合芍药汤治疗,比较2组患者疗效;排便次数恢复正常时间、大便性状恢复正常时间、肠道黏膜水肿减轻时间、溃疡痊愈时间;治疗前后腹痛、黏液脓血便、腹泻症状积分以及不良反应发生率。结果显示,观察组患者治疗总有效率高于对照组(P<0.05),观察组患者排便次数恢复正常时间、大便性状恢复正常时间、肠道黏膜水肿减轻时间、溃疡痊愈时间均短于对照组(P<0.05),观察组患者腹痛、黏液脓血便、腹泻症状积分均低于对照(P<0.05),观察组不良反应发生率低于对照组(P<0.05)。结果表明,对溃疡性结肠炎患者实施中医治疗效果确切,可有效加速患者症状消失,缩短疗程,且可减少单纯西药治疗的不良反应,值得临床推广应用。

This study was to observe the effect of ulcerative colitis(UC)treated with integration of TCM and western medicines,randomly divided 70 UC patients into control group(35 cases,adopted western drugs as methylprednisolone,etc)and observation group(35 cases,based on control group,added with Shaoyao Tang,a TCM formula,shortened to Tang),then compared both groups’effect;the time of defecation frequency recovered to normal one,of stool characters turned to normal situation,of bowel mucosa edema relieved,and of ulcer cured;the score rating of abdominal pain,of mucous and bloody purulent stool and of diarrhea before and after treatment;and untoward reaction incidence.As results,in total effective rate,in the time of above-mentioned each symptoms changed,in the score ratings of above-mentioned each symptoms,and untoward reaction incidence,observation groups was respectively higher,shorter,lower,and lower than control group(all,P<0.05).Results show that UC treated with integration of TCM and western medicine can achieve certain effect,effectively accelerate symptoms fastly disappeared,shorten treatment course,and reduce the untoward reaction induced by alone western medicine.It is worthy of clinical popularization and application.