摘要
Microwave-induced thermoacoustic imaging(MI-TAI)remains one of the focus of attention among biomedical imaging modalities over the last decade.However,the transmission and dis-tribution of microwave inside bio-tissues are complicated,thus result in severe artifacts.In this study,to reveal the underlying mechanisms of artifacts,we deeply investigate the distribution of specific absorption rate(SAR)inside tissue-mimicking phantoms with varied morphological features using both mathematical simulations and corresponding experiments.Our simulated results,which are confirmed by the associated experimental results,show that the SAR distri-bution highly depends on the geometries of the imaging targets and the polarizing features of the microwave.In addition,we propose the potential mechanisms including Mie-scattering,Fabry-Perot-feature,small curvature effect to interpret the diffraction effect in different scenarios,which may provide basic guidance to predict and distinguish the artifacts for TAI in both fundamental and clinical studies.
基金
This study was supported by the National Natural Science Foundation of China(Nos.62022037,61775028,81571722,61528401 and 61921002)
Guangdong province(2019ZT08Y191)
Shenzhen Science and Technology Program(KQTD20190929172743294)
Startup grant from Southern University of Science and Technology.