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右美托咪啶用于小儿尿道下裂手术的镇静最适剂量

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摘要 目的研究右美托咪啶用于小儿尿道下裂手术的镇静的最适剂量.方法选择唐山妇幼保健院收治的60例会阴型尿道下裂手术患儿,均接受喉罩静吸复合全麻,采纳"麻醉差异性"随机分为低剂量组(1.5 ug/kg滴鼻)、中剂量组(2.0 ug/kg滴鼻)、高剂量组(2.5 ug/kg滴鼻),每组20例,三组麻醉效果比较.结果术后2 h、4 h、8 h PFS评分高剂量组明显比低剂量组低,Ramsay评分比低剂量组高,P<0.05;高剂量组PFS评分、Ramsay评分与中剂量组比较,P>0.05;高剂量组、中剂量组比较不良反应发生率有统计学差异,P<0.05;中剂量组、低剂量组比较不良反应发生率无统计学差异,P>0.05.结论2.0 ug/kg右美托咪啶滴鼻用于小儿尿道下裂手术中,镇静效果确切,不良反应发生率低,安全性高,可作为手术的最佳用药剂量、具有较高的临床价值.
出处 《中国急救复苏与灾害医学杂志》 2020年第S01期63-64,共2页 China Journal of Emergency Resuscitation and Disaster Medicine
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