广州市荔湾区2006年登革热疫情流行病学特征分析

The epidemiological characteristics of Dengue fever in Liwan district of Guangzhou city in 2006

目的分析广州市荔湾区2006年登革热疫情流行病学特征,探讨预防控制措施.方法对各医院报告的病例进行流行病学个案调查;采集病例血样作血清学或病原学检测;对疫点进行蚊媒调查,在疫点周围开展病例搜索.共接报350例病例(包括疑似病例),采集336份血标本进行血清学检测,检出登革热IgM和(或)IgG阳性296份,其中12例分离到登革热病毒;共对176个疫点进行处理.结果广州市荔湾区2006年共报告登革热病例310例,发病率为43.66/10万(按户籍人口计算),无死亡病例;疫情涉及20个行政街,有4个暴发点;流行季节为7月上旬至11月中旬,高峰在8月下旬和9月上旬;病毒为登革Ⅰ型;男性177例,女性133例,性别比1.33∶1;发病年龄最大为78岁,最小为3岁,以青壮年为主,20~39岁136例,占43.87%.结论该区存在有利登革热流行的自然、社会因素,预防控制是一项长期、复杂的工作,今后要加强疫情预测预报,加快老城区和城中村的改造.

Objective To study the epidemiological characteristics of Dengue fever in Liwan district of Guangzhou city in 2006 and explore the prevention and control strategy.Methods A case-study was conducted based on patients notified by hospitals.The serum samples were collected from the reported cases for the detection of anti-dengue virus antibodies and dengue virus.The mosquito vector at epidemic spot was investigated and cases were further identified at the epidemic spots.A total of 350 cases were reported (including suspected cases),and 336 blood samples were collected for serum testing.The detection of dengue IgM and(or)IgG was 296.Of which,dengue virus Was isolated in 12 cases,and preventive measures have been taken at 176 epidemic spots.Results There was 310 cases of dengue fever in Liwan district of Guangzhou city in 2006.The incidence rate was 4.366 per ten thousand(according to the census register population)and no death toll.The epidemic situation was involved 20 streets and 4 outbreak spots.The epidemic season was from the first ten day of July to the middle of November,and the peak epidemic season was from the last third of August to the first ten days of September.The dengue isolated was belong to type Ⅰ.old and the youngest was 3,most of the patients were the middle-aged and 136 patients were from 20 to 39 years old accounting for 43.87%.Conclusion The epidemic situation in this district was related to the local natural environment and social factors.The prevention and control against dengue fever would be a long-term work.It is necessary to strengthen the prediction of dengue fever and speed up the old city restoration and sanitation improvement.