网膜素-1与缺血性脑卒中相关关系的研究进展

Advances in the Relationship Between Omentin-1 and Ischemic Stroke

缺血性脑卒中作为常见的神经系统疾病,与动脉粥样硬化、高血压、糖尿病均有一定程度的相关性.目前新型脂肪因子正在深入研究中,其中网膜素-1(omentin-1)是一种由内脏脂肪组织产生的脂肪因子,参与了动脉粥样硬化等疾病的病理过程,有抗炎、抗动脉粥样硬化等作用.该文旨在阐明omentin-1对缺血性脑卒中的作用,可能在不同方面潜在地成为其生物标志物、药物、靶标.

Stroke,as a common neurological disease,is associated with atherosclerosis,hypertension and diabetes mellitus to some extent.At present,new adipokines are under in-depth study,among which omentin-1 is an adipokines produced by visceral adipose tissue,which has anti-inflammatory and anti-atherosclerosis effects.The purpose of this study was to elucidate the role of omentin-1 in ischemic stroke,which may be a potential biomarker,drug and target in different aspects.