维持性血液透析患者合并膀胱癌患者治疗方法及效果评价

Evaluation of the Therapeutic Methods and Effects of Maintenance Hemodialysis Patients with Bladder Cancer

目的探究维持性血液透析患者合并膀胱癌患者治疗方法,并对治疗效果进行评价.方法随机选取2011年1月至2014年3月我院60例维持性血液透析合并膀胱癌患者,随机分为两组,对照组进行局部肿瘤切除,术后进行化疗,对照组进行根治性膀胱切除术,记录两组术中死亡率、手术指标、随访5年生存率.结果两组患者均无发生术中死亡,实验组术中指标、术后恢复及生存质量均优于对照组,差异具有统计学意义(P<0.05),5年随访后实验组、对照组生存率分别为73.33%及70.00%,差异无统计学意义(P>0.05).结论维持性血液透析患者膀胱癌发生率随着透析时间的增加而增加,患者接受部分肿瘤切除术与根治性膀胱切除术后远期生存率差异不明显,但是部分肿瘤切除手术指标、术后恢复、患者生存质量相对全切组较优.

Objective This paper aims to explore the treatment of maintenance hemodialysis patients with bladder cancer and evaluate the therapeutic effect.Methods From January 2011 to March 2014,60 patients with maintenance hemodialysis com-bined with bladder cancer in our hospital were randomly divided into two groups.The control group underwent local tumor resec-tion,postoperative chemotherapy,and the control group underwent radical cystectomy.The intraoperative mortality,surgical in-dicators and 5-year survival rate were recorded.Results There was no intraoperative death in the two groups,and the intraopera-tive indexes,postoperative recovery and quality of life in the experimental group were better than those in the control group,the difference was staistically significant(P<0.05).Afer five-year follow-up,the survival rates of the experimental group and the control group were 73.33%and 70.00%,respectively,and the difference was not stistically significant(P>0.05).Conclu-sion The incidence of bladder cancer in maintenance hemodialysis patients increases with the increase of dialysis time.There is no significant difference in the long-term survival rate after partial tumor resection and radical cystectomy,but the indicators of partial tumor resection,postoperative recovery and quality of life of patients are better than that of total resection group.