2019-2022年深圳口岸进出口食品中沙门氏菌的血清分型与耐药情况分析

Serotyping and drug resistance of Salmonella in imported and exported food at Shenzhen Port from 2019 to 2022

目的了解2019—2022年深圳口岸进出口食品中检出沙门氏菌的血清分型与耐药情况。方法选用27株于2019年至2022年深圳口岸海关进出口食品中检出的沙门氏菌进行抗原血清鉴别与药敏分析。结果2019—2022年深圳进出口检出沙门氏菌的食品中无明显优势血清,但水产品中的沙门氏菌优势血清为韦太夫雷登。在进口食品中有数种国内罕见的血清型,但仍在常见的O群中。用美国临床和实验室标准化协会标准和欧洲药敏试验委员会标准对于沙门氏菌或肠杆菌科流行病学折点进行比较判堢,喹诺酮类对大多数菌株有一堢的作用,大多数菌株对叶酸代谢途径抑制剂敏感。多种耐药因子的出现使得沙门氏菌对药物的敏感性不断下降,出现对各大类抗生素多重耐药的“超级”菌,只有少数几种抗菌药物仍对大多数菌株有效。结论深圳进出口与本地近年检出的沙门氏菌无明显优势血清,但耐药性不断增强。沙门氏菌耐药性与年份和进出口原产地相关,与血清型无明显关系。

Objective To investigate the serotyping and drug resistance of Salmonella detected in imported and exported food at Shenzhen Port from 2019 to 2022.Methods Twenty-seven strains of Salmonella detected in imported and exported food from Shenzhen Port customs from 2019 to 2022 were selected for antigenic serum identification and drug susceptibility analysis.Results There was no obvious dominant serum in all foods of Salmonella detected in Shenzhen’s import and export from 2019 to 2022,but the dominant serum of Salmonella in aquatic products was vetteflieden.There were several domestic rare serotypes in imported foods,but they were still in the common group O.There were several rare serotype in imported food,but they were still in the common O group.According to the standards of the American Association for Clinical and Laboratory Standardization and the European Commission for Drug Sensitivity Testing,the epidemiological break points of Salmonella or Enterobacteriaceae were compared and determined.Quinolones had certain effects on most strains,and most strains were sensitive to folic acid metabolic pathway inhibitors.The emergence of multiple antibiotic resistance factors had led to a continuous decrease in the sensitivity of Salmonella to drugs,leading to the emergence of“super”bacteria with multiple antibiotic resistance in various categories,only a few antibacterial drugs were still effective for most strains.Conclusion There is no obvious superiority in the serum of Salmonella detected in Shenzhen and local in recent years,but the drug resistance is increasing.The drug resistance of Salmonella is related to the year and the origin of import and export,but has no obvious relationship with serotype.