肠道菌群与系统性红斑狼疮的相关性

The relationship between intestinal flora and systemic lupus erythematosus

越来越多的报道阐述了活动性系统性红斑狼疮(SLE)患者肠道菌群及其相关代谢途径存在异常,表现为其肠道细菌多样性降低。探讨肠道菌群与系统性红斑狼疮(SLE)的相关性对进一步研究系统性红斑狼疮的发病机制及寻找新的治疗方案具有一定的参考价值。菌群移植有可能成为临床调节肠道菌群紊乱,治疗系统性红斑狼疮的一种有效手段。

An increasing number of reports describe the abnormality of the gut microbiota and its associated metabolic pathways in patients with active systemic lupus erythematosus(SLE),manifesting as decreased gut bacterial diversity.Exploring the correlation between intestinal flora and systemic lupus erythematosus(SLE)holds certain reference value for further research on the pathogenesis of systemic lupus erythematosus and finding new treatment options.Fecal microbiota transplantation may become an effective approach in clinically modulating gut microbiota dysbiosis and treating systemic lupus erythematosus.