摘要
Lignin is one of the most widespread organic compounds found on earth,boasting a wealth of aromatic molecules.The use of lignin feedstock for biochemical productions is of great importance for achieving"carbon neutrality."In recent years,a strategy for lignin valorization known as the"bio-funnel"has been proposed as a means to generate a variety of commercially valuable chemicals from lignin-derived compounds.The implementation of biocatalysis and metabolic engineering techniques has substantially advanced the biotransformation of depolymerized lignin into chemicals and materials within the supply chain.In this review,we present an overview of the latest advancements in microbial upcycling of depolymerized lignin into value-added chemicals.Besides,the review provides insights into the problems facing current biological lignin valorization while proposing further research directions to improve these technologies for the extensive accomplishment of the lignin upcycling.
基金
supported by the National Key Research and Development Program of China(2022YFC2104600)
the National Natural Science Foundation of China(nos.32270087,32241040,and 31970314)
the Natural Science Foundation of Fujian Province of China(no.2020J05011)
Guangdong Basic and Applied Basic Research Foundation(no.2021A1515110340)
Xiamen University(no.0660X2510200)
the Fundamental Research Funds for the Central Universities(no.20720220086),and ZhenSheng Biotech.
