高分辨率磁共振血管壁成像联合磁共振弥散加权成像在宫颈癌中的诊断研究

Study on HRMR-VWI Combined with DWI-MRI in the Diagnosis of Uterine Cervical Carcinoma

目的:探讨高分辨率磁共振血管壁成像(HRMR-VWI)联合磁共振弥散加权成像(DWI-MRI)在宫颈癌(UCC)中的诊断价值.方法:选择2020年10月至2021年10月固始县第三人民医院收治的90例高度疑似UCC患者为研究对象,所有患者入院时接受HRMR-VWI、DWI-MRI检查,并择期行宫颈组织活检,以宫颈组织活检结果为"金标准",分析HRMR-VWI联合DWI-MRI在UCC中的诊断价值.结果:90例高度疑似UCC患者,经宫颈组织活检检查,确诊52例,占比57.78%,其中鳞癌42例(80.77%),腺癌10例(19.23%);HRMR-VWI联合DWI-MRI诊断UCC的敏感度、准确度均高于HRMR-VWI、DWI-MRI单独检查,差异有统计学意义(P<0.05);HRMR-VWI、DWI-MRI单独诊断UCC与宫颈组织活检结果一致性一般(Kappa=0.690、0.734),二者联合检查诊断UCC与宫颈组织活检结果一致性较好(Kappa=0.908).结论:HRMR-VWI联合DWI-MRI诊断UCC的敏感度及准确度较高,与宫颈组织活检结果一致性较好.

Objective:To investigate the diagnostic value of high resolution-magnetic resonance vessel wall imaging(HRMR-VWI)combined with diffusion-weighted imaging-magnetic resonance imaging(DWI-MRI)in uterine cervical carcinoma(UCC).Methods:Ninety patients with highly suspected UCC treated in Gushi County Third People's Hospital from October 2020 to October 2021 were selected as the research subjects.All patients were examined by HRMR-VWI and DWI-MRI at admission,and the cervical tissue biopsy was performed at a selected time.The results of cervical tissue biopsy were regarded as the'gold standard'.The diagnostic value of HRMR-VWI combined with DWI-MRI in UCC was analyzed.Results:Among the 90 patients with highly suspected UCC,52 cases were diagnosed by cervical biopsy,accounting for 57.78%,of which there were 42 cases of squamous cell earcinoma(80.77%)and 10 cases of adenocarcinoma(19.23%).The sensitivity and accuracy of HRMR-VWI combined with DWI-MRI in the diagnosis of UCC were higher than those of HRMR-VWI and DWI-MRI alone,the difference was statistically significant(P<0.05).The results of HRMR-VWI and DWI-MRI in the single diagnosis of UCC were generally consistent with those of cervical biopsy(Kappa=0.690,0.734),and the results of the two in the combined diagnosis of UCC were greatly consistent with those of cervical biopsy(Kappa=0.908).Conclusion:HRMR-VWI combined with DWI-MRI has high sensitivity and accuracy in the diagnosis of UCC,and the results are highly consistent with cervical biopsy.