血清D-D水平与子痫前期患者早产儿发生的相关性

Correlation between Serum D-D Level and Preterm Infants in Patients with Preeclampsia

目的:探讨血清D-二聚体(D-D)水平与子痫前期(PE)患者早产儿发生的相关性.方法:选取我院2018年8月至2020年8月收治的100例PE患者.入院时检测患者血清D-D及其他凝血指标,对PE患者随访至分娩,记录早产儿发生情况,分析血清D-D水平与PE患者早产儿发生的相关性.结果:100例PE患者中有早产儿48例,占48.00%(48/100);发生组血清D-D[(3.97±1.01)μg/ml]水平高于未发生组[(3.12±0.86)μg/ml](P<0.05);两组其他基线资料比较,差异无统计学意义(P>0.05);经Logistic回归分析结果显示,血清D-D水平高表达与PE患者早产儿发生密切相关(OR>1,P<0.05).结论:血清D-D水平与PE患者早产儿发生密切相关,血清D-D水平高表达,提示PE患者发生早产的风险较高.

Objective:To examine the relationship between serum D-dimer(D-D)levels and preterm births in preeclampsia(PE)patients.Methods:We chose 100 patients with PE who were treated in our hospital between August 2018 and August 2020.At admission,patients'serum D-D and other coagulation indexes were measured;PE patients were followed until delivery;the occurrence of preterm infants was recorded;and the correlation between serum D-D level and premature infants in patients with PE was analyzed.Results:There were 48 preterm infants among 100 patients with PE,accounting for 48.00 percent(48/100);the level of serum D-D was significantly higher in the occurrence group[(3.97±1.01)g/ml]than in the non-occurrence group[(3.12±0.86)g/ml](P<0.05);there was no statistically significant difference in other baseline data between the two groups(P>0.05);the results of logistic regression analysis indicated that the high expression of serum D-D level was significantly associated with the occurrence of preterm infants in patients with PE(OR>1,P<0.05).Conclusion:Serum D-D levels are strongly associated with the occurrence of preterm infants in patients with PE;thus,a high serum D-D level indicates that PE patients are at an increased risk of preterm delivery.