吸烟与男性新兵肾小球高滤过的相关性分析

Correlation analysis between smoking and glomerular hyperfiltration in male recruits

目的分析吸烟与男性新兵肾小球高滤过的相关性.方法横断面研究某部2023年1898名男性新兵,依据不同吸烟状态、不同估算肾小球滤过率分类,通过二分类多元logistic回归分析评估对估算肾小球滤过率的影响.结果单因素分析显示,估算肾小球滤过率与吸烟、吸烟指数、体重指数、收缩压、舒张压、心率、红细胞、肌酐存在统计学意义(P<0.05).多元logistic回归分析显示,相比不吸烟者,吸烟与肾小球高滤过独立相关(OR=2.029,95%CI:1.104~3.731),肾小球高滤过概率呈2倍以上;较轻度吸烟指数者,重度吸烟指数与估算肾小球滤过率相关(OR=2.497,95%CI:1.010~6.175).结论吸烟是男性入伍新兵估算肾小球滤过率的影响因素,与肾小球高滤过独立相关.

Objective To analyze the correlation between smoking and glomerular hyperfiltration in male recruits.Methods A cross-sectional study was conducted on 1898 male recruits in a military unit in 2023,who were classified according to different smoking status and different estimated glomerular filtration rate,and the influence on estimated glomerular filtration rate was evaluated by binary logistic regression analysis.Results Univariate analysis showed that the estimated glomerular filtration rate was statistically significant with smoking,smoking index,body mass index,systolic blood pressure,diastolic blood pressure,heart rate,red blood cell count,and serum creatinine(P<0.05).Multivariate logistic regression analysis showed that smoking was independently associated with glomerular hyperfiltration compared with non-smokers(OR=2.029,95%CI:1.104-3.731),the probability of glomerular hyperfiltration was more than 2 times.Compared with mild smoking index,heavy smoking index was associated with glomerular hyperfiltration(OR=2.497,95%CI:1.010-6.175).Conclusions Smoking is an influencing factor in estimating glomerular filtration rate in male recruits and is independently associated with glomerular hyperfiltration.