摘要
Hepatitis B virus(HBV)infection leads to severe liver disease and is one of the main causes of hepatocellular carcinomarelated mortality.Although the prevalence of HBV infection has decreased markedly with the effective application of vaccines,it's still an arduous task to clear the hepatitis B surface antigen after routine antiviral therapy,as the viral rebound often occurs after therapy withdrawal.Therefore,the situation of dealing with HBV infection is still challenging.As such,eliminating HBV infection has become an important task for governments all over the world.In 2016,the Global Health Sector Strategy on Viral Hepatitis was approved by the World Health Assembly to eliminate the HBV infection by 2030.
