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Hepatic Encephalopathy: An Update on the Pathophysiology and Therapeutic Options 被引量:19

Hepatic Encephalopathy: An Update on the Pathophysiology and Therapeutic Options
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摘要 Hepatic encephalopathy is a spectrum of reversible neuropsychiatric abnormalities,seen in patients with liver dysfunction and/or portosystemic shunting.One of the most debilitating complications of cirrhosis,encephalopathy affects 30-45% of cirrhotics.In addition to significantly affecting the lives of patients and their caregivers,it is also associated with increased morbidity and mortality as well as significant utilization of health care resources.In this paper,we provide an overview on the pathophysiology,diagnosis,management and newer therapies of hepatic encephalopathy. Hepatic encephalopathy is a spectrum of reversible neuropsychiatric abnormalities,seen in patients with liver dysfunction and/or portosystemic shunting.One of the most debilitating complications of cirrhosis,encephalopathy affects 30-45% of cirrhotics.In addition to significantly affecting the lives of patients and their caregivers,it is also associated with increased morbidity and mortality as well as significant utilization of health care resources.In this paper,we provide an overview on the pathophysiology,diagnosis,management and newer therapies of hepatic encephalopathy.
出处 《Journal of Clinical and Translational Hepatology》 SCIE 2017年第2期142-151,共10页 临床与转化肝病杂志(英文版)
关键词 Hepatic encephalopathy CIRRHOSIS LACTULOSE RIFAXIMIN Hepatic encephalopathy Cirrhosis Lactulose Rifaximin
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