期刊文献+

Nonalcoholic Fatty Liver Disease: Dyslipidemia, Risk for Cardiovascular Complications, and Treatment Strategy 被引量:23

Nonalcoholic Fatty Liver Disease: Dyslipidemia, Risk for Cardiovascular Complications, and Treatment Strategy
原文传递
导出
摘要 Studies have shown that nonalcoholic fatty liver disease (NAFLD) is strongly associated with several metabolic disorders and diseases,such as obesity,type 2 diabetes mellitus,and dyslipidemia.In NAFLD,dyslipidemia is manifested as increased serum triglyceride and low-density lipoprotein cholesterol levels and decreased high-density lipoprotein cholesterol levels,all of which are key risk factors for cardiovascular disease (CVD).CVD is a leading cause of mortality in NAFLD patients.Thus,implementation of an aggressive therapeutic strategy for dyslipidemia with hypolipidemic agents may mitigate the risk for CVD among NAFLD patients.Here,we provide a current review of literature regarding NAFLD,with particular emphasis on dyslipidemia and available treatment options. Studies have shown that nonalcoholic fatty liver disease (NAFLD) is strongly associated with several metabolic disorders and diseases,such as obesity,type 2 diabetes mellitus,and dyslipidemia.In NAFLD,dyslipidemia is manifested as increased serum triglyceride and low-density lipoprotein cholesterol levels and decreased high-density lipoprotein cholesterol levels,all of which are key risk factors for cardiovascular disease (CVD).CVD is a leading cause of mortality in NAFLD patients.Thus,implementation of an aggressive therapeutic strategy for dyslipidemia with hypolipidemic agents may mitigate the risk for CVD among NAFLD patients.Here,we provide a current review of literature regarding NAFLD,with particular emphasis on dyslipidemia and available treatment options.
出处 《Journal of Clinical and Translational Hepatology》 SCIE 2015年第1期78-84,共7页 临床与转化肝病杂志(英文版)
关键词 Nonalcoholic fatty liver disease DYSLIPIDEMIA Cardiovascular disease Hypolipidemic agents Nonalcoholic fatty liver disease Dyslipidemia Cardiovascular disease Hypolipidemic agents
  • 相关文献

参考文献2

二级参考文献25

  • 1Mohamed H Ahmed,Christopher D Byrne.Obstructive sleep apnea syndrome and fatty liver: Association or causal link?[J].World Journal of Gastroenterology,2010,16(34):4243-4252. 被引量:8
  • 2Yu-Cheng Lin,Huey-Ming Lo,Jong-Dar Chen.Sonographic fatty liver, overweight and ischemic heart disease[J].World Journal of Gastroenterology,2005,11(31):4838-4842. 被引量:11
  • 3N Assy,I Bekirov,Y Mejritsky,L Solomon,S Szvalb,O Hussein.Association between thrombotic risk factors and extent of fibrosis in patients with non-alcoholic fatty liver diseases[J].World Journal of Gastroenterology,2005,11(37):5834-5839. 被引量:4
  • 4Amedeo Lonardo,Silvia Lombardini,Federica Scaglioni,Stefano Ballestri,Anna Maria Verrone,Marco Bertolotti,Lucia Carulli,Dorval Ganazzi,Nicola Carulli,Paola Loria.Fatty liver,carotid disease and gallstones:A study of age-related associations[J].World Journal of Gastroenterology,2006,12(36):5826-5833. 被引量:14
  • 5Selim G?k?e,Zehra Atbinici,Zehra Aycan,Hasibe G?k?e ??nar,Pelin Zorlu.The Relationship Between Pediatric Nonalcoholic Fatty Liver Disease and Cardiovascular Risk Factors and Increased Risk of Atherosclerosis in Obese Children[J]. Pediatric Cardiology . 2013 (2)
  • 6Giuseppe Mancia,Robert Fagard,Krzysztof Narkiewicz,Josep Redon,Alberto Zanchetti,Michael B?hm,Thierry Christiaens,Renata Cifkova,Guy De Backer,Anna Dominiczak,Maurizio Galderisi,Diederick E. Grobbee,Tiny Jaarsma,Paulus Kirchhof,Sverre E. Kjeldsen,Stéphane Laurent,Athanasios J. Manolis,Peter M. Nilsson,Luis Miguel Ruilope,Roland E. Schmieder,Per Anton Sirnes,Peter Sleight,Margus Viigimaa,Bernard Waeber,Faiez Zannad,Josep Redon,Anna Dominiczak,Krzysztof Narkiewicz,Peter M. Nilsson.2013 ESH/ESC Guidelines for the management of arterial hypertension[J]. European Heart Journal . 2013 (28)
  • 7Derrick M. Van Rooyen,Lay T. Gan,Matthew M. Yeh,W. Geoffrey Haigh,Claire Z. Larter,George Ioannou,Narci C. Teoh,Geoffrey C. Farrell.Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome<!-- Doctopic: GMD -->[J].Journal of Hepatology.2013(1)
  • 8Marcello Ricardo Paulista Markus,Sebastian Edgar Baumeister,Jan Stritzke,Marcus D?rr,Henri Wallaschofski,Henry V?lzke,Wolfgang Lieb.Hepatic Steatosis Is Associated With Aortic Valve Sclerosis in the General Population: The Study of Health in Pomerania (SHIP)[J].Arteriosclerosis Thrombosis and Vascular Biology.2013(7)
  • 9Matti J. Tikkanen,Rana Fayyad,Ole Faergeman,Anders G. Olsson,Chuan-Chuan Wun,Rachel Laskey,John J. Kastelein,Ingar Holme,Terje R. Pedersen.Effect of intensive lipid lowering with atorvastatin on cardiovascular outcomes in coronary heart disease patients with mild-to-moderate baseline elevations in alanine aminotransferase levels[J].International Journal of Cardiology.2013
  • 10Giovanni Targher,Christopher D. Byrne.Nonalcoholic Fatty Liver Disease: A Novel Cardiometabolic Risk Factor for Type 2 Diabetes and Its Complications[J].The Journal of Clinical Endocrinology & Metabolism.2013(2)

共引文献69

同被引文献130

引证文献23

二级引证文献150

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部