摘要
Objective:To assess the resistance against widely used antibiotics in case of Acinetobacter baumannii(A.baumannii)infection.Methods:A total of 350 samples of pus,urine,swab and others from different patients were examined and the bacterial growth appeared in 50 samples.Each sample was inoculated on blood,MacConkey and cystine lactose electrolyte deficient agar.The antimicrobial susceptibility profile of the isolates was determined using agar plate method/disk-diffusion method(modified-Kirby Baur disc diffusion method).Results:In current study,a large number of isolates of A.baumannii obtained from different specimens were resistant to avelox(56%),followed by tygacil(46%),augmentin(46%),cefspan(38%),cefixime(24%)and ampicillin(20%).However,the antibiogram of A.baumannii also showed that most of the isolates(88%)were highly sensitive to cefalexin.Second maximum sensitivity of A.baumannii was seen to amikacin(84%).The sensitivity of isolates against amikacin was followed by ticarcillin(80%).Meronem was found highly active against the tested isolates(78%).Sensitivity was observed for tienem(76%),sulzone(72%)followed by azactam(68%),cefobid(66%)to cefotaxime(66%)and ciproxin(62%).Conclusions:Results elucidate that A.baumannii is a severe problem as it has become a highly resistant species in hospitalized patients and resistant A.baumannii infection turned out to have increased all-cause mortality.
