摘要
Objective:To evaluate leaves extract of Azima tetracantha and Gmelina asiatica for lethality to brine shrimp larvae(Artemia salina and Artemia fransiscana).Methods:The plant materials were extracted based on polarity gradients of petroleum ether,benzene,chloroform,acetone,ethanol and methanol.The extracts were investigated for their cytotoxic potential.Results:In the brine shrimp lethality assay of all extracts,exception of acetone,ethanol and petroleum ether extracts Gmelina asiatica displayed 100%mortality at 1000μg/mL by Artemia salina and Artemia fransiscana.Chloroform extract was the most potent and presented the highest percentage of mortality with the lowest LC_(50)values by both assay too.Conclusions:The results of the present study suggest the presence of photochemical possessing cytotoxic agents.
