益肾通脉膏方联合常规治疗对脑梗死患者神经功能恢复的疗效观察

The Therapeutic Effect of Yishen Tongmai Gao Combined with Conventional Treatment on the Recovery of Neurological Function in Patients with Cerebral Infarction

目的探讨益肾通脉膏方联合常规治疗在脑梗死中的应用效果。方法选取我院2021年5月—2023年5月收治的70例脑梗死患者为研究对象,按随机数字表法将其分为对照组与观察组,各35例。对照组采用常规西药治疗,观察组在对照组基础上加用益肾通脉膏方治疗,两组均持续治疗14 d。比较两组患者的临床疗效、神经功能、血液流变学指标及不良反应发生情况。结果观察组治疗总有效率为94.29%,高于对照组的77.14%,差异有统计学意义(P<0.05)。治疗14 d后,神经功能缺损评分为(7.05±1.12)分,低于对照组的(8.98±1.14)分,差异有统计学意义(P<0.05);观察组纤维蛋白原、红细胞压积、全血高切黏度及全血低切黏度水平分别为(2.31±0.37)g/L、(41.05±4.08)%、(5.49±1.02)mPa·s、(7.18±1.04)mPa·s,均低于对照组的(2.85±0.41)g/L、(44.51±4.13)%、(6.35±1.06)mPa·s、(8.55±1.11)mPa·s,组间差异有统计学意义(P<0.05)。两组不良反应发生率相比,差异无统计学意义(P>0.05)。结论益肾通脉膏方联合常规治疗可加快脑梗死患者神经功能恢复,纠正血液流变学指标,安全可靠。

Objective To explore the application effect of Yishen Tongmai Gao combined with conventional treatment in the treatment of cerebral infarction.Methods 70 patients with cerebral infarction admitted to our hospital from May 2021 to May 2023 were selected as the study objects,and were divided into a control group and an observation group according to random number table method,with 35 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with Yishentongmai cream on the basis of the control group.Both groups were treated for 14 days.The clinical efficacy,neurological function,hemorheology indexes and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.29%,higher than 77.14%of the control group,and the difference was statistically significant(P<0.05).14 days after treatment,the score of neurological impairment was(7.05±1.12)points,lower than(8.98±1.14)points of the control group,the difference was statistically significant(P<0.05);the levels of fibrinogen,hematocrit,whole blood high shear viscosity and whole blood low shear viscosity in the observation group were(2.31±0.37)g/L,(41.05±4.08)%,(5.49±1.02)mPa·s and(7.18±1.04)mPa·s,respectively,they were lower than(2.85±0.41)g/L,(44.51±4.13)%,(6.35±1.06)mPa·s,(8.55±1.11)mPa·s in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of Yishen Tongmai Gao and conventional treatment can accelerate the recovery of neurological function in patients with cerebral infarction,correct hemorheological indicators,and is safe and reliable.