自拟健脾化湿方联合益生菌对泄泻型肠易激综合征患者中医证候及病情改善的影响

Effect of Self-Made Jianpi Huashi Prescription Combined with Probiotics on TCM Symptoms and Condition Improvement of Patients with Diarrhea Type Irritable Bowel Syndrome

目的分析自拟健脾化湿方联合益生菌对泄泻型肠易激综合征患者中医证候及病情改善的影响.方法选取本院2020年1月—2022年10月收治的80例泄泻型肠易激综合征患者为研究对象,根据随机数字表法分为两组.对照组(n=40)采用益生菌治疗,观察组(n=40)采用自拟健脾化湿方联合益生菌治疗.比较两组患者的中医证候积分、生活质量及临床疗效.结果治疗后,观察组的中医证候积分中主症、次症及总积分分别为(1.17±0.45)分、(1.91±0.51)分、(3.08±0.96)分,均低于对照组的(2.53±0.62)分、(2.15±0.63)分、(4.68±1.25)分,组间差异有统计学意义(P<0.05).治疗后,观察组的肠易激综合征生活质量量表中各维度评分均高于对照组,组间差异有统计学意义(P<0.05).观察组的治疗总有效率为92.50%,高于对照组的75.00%,差异有统计学意义(P<0.05).结论泄泻型肠易激综合征患者采用自拟健脾化湿方联合益生菌治疗的效果显著,可改善中医证候积分,提高生活质量,值得临床推广使用.

Objective To analyze the effect of self-made Jianpi Huashi Prescription combined with probiotics on TCM syndromes and condition improvement of patients with diarrhea type irritable bowel syndrome.Methods 80 patients with diarrhea type irritable bowel syndrome admitted to the hospital from January 2020 to October 2022 were selected as the research objects and were divided into two groups according to random number table method.The control group(n=40)was treated with probiotics,and the observation group(n=40)was treated with self-made Jianpi Huashi Prescription combined with probiotics.The TCM syndrome score,quality of life and clinical efficacy of the two groups were compared.Results After treatment,the main disease,secondary disease and total score of TCM syndrome scores in the observation group were(1.17±0.45)points,(1.91±0.51)points and(3.08±0.96)points,respectively,which were lower than(2.53±0.62)points,(2.15±0.63)points and(4.68±1.25)points in the control group,the differences between the groups were statistically significant(P<0.05).After treatment,the scores of irritable bowel syndrome quality of life scale in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05).The total effective rate of the observation group was 92.50%,which was higher than 75.00%of the control group,the difference was statistically significant(P<0.05).Conclusion The self-made Jianpi Huashi Prescription combined with probiotics is effective in the treatment of patients with diarrhea type irritable bowel syndrome,which can improve the TCM syndrome scores and improve the quality of life,and is worthy of clinical promotion.