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增强型体外反搏治疗联合曲美他嗪对冠心病支架术后患者心功能及微循环功能的影响

Effect of Enhanced External Counterpulsation Combined with Trimetazidine on Cardiac Function and Microcirculation in Patients with Coronary Heart Disease after Stenting
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摘要 目的探讨增强型体外反搏(EECP)联合曲美他嗪治疗冠心病(CHD)支架术后患者的效果.方法选取2019年10月—2021年11月本院收治的72例CHD支架术后患者为研究对象,以随机数字表法分为两组,每组36例.对照组采用曲美他嗪治疗,观察组采用EECP联合曲美他嗪治疗,均持续治疗3个月.比较两组患者的临床疗效、心功能指标及心肌微循环功能.结果观察组的临床总有效率为91.67%,高于对照组的72.22%,差异有统计学意义(P<0.05).治疗后,观察组的左室舒张末期内径、左室收缩末期内径分别为(46.62±3.15)mm、(45.44±2.52)mm,均短于对照组的(50.85±3.27)mm、(49.39±3.31)mm,左室射血分数为(56.29±3.73)%,高于对照组的(51.64±3.49)%,组间差异有统计学意义(P<0.05).治疗后,观察组的心肌微循环阻力指数指数为(29.48±1.53)U,低于对照组的(32.21±1.47)U,差异有统计学意义(P<0.05).结论CHD支架术后患者采用EECP疗法联合曲美他嗪治疗,能有效改善心功能及微循环功能,增强临床疗效. Objective To investigate the effect of enhanced external counterpulsation(EECP)combined with trimetazidine on patients with coronary heart disease(CHD)after stenting.Methods 72 patients admitted to the hospital after CHD stenting from October 2019 to November 2021 were selected as the research objects and were divided into two groups by random number table method,with 36 patients in each group.The control group was treated with trimetazidine,and the observation group was treated with EECP combined with trimetazidine.Both groups were treated for 3 months.The clinical efficacy,cardiac function indexes and myocardial microcirculation function were compared between the two groups.Results The total clinical effective rate of the observation group was 91.67%,which was higher than 72.22%of the control group,the difference was statistically significant(P<0.05).After treatment,the left ventricular end-diastolic diameter and left ventricular end-systolic diameter of the observation group were(46.62±3.15)mm and(45.44±2.52)mm,respectively,which were shorter than(50.85±3.27)mm and(49.39±3.31)mm of the control group,and the left ventricular ejection fraction was(56.29±3.73)%,which was higher than(51.64±3.49)%of control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the myocardial index of microcirculatory resistance of the observation group was(29.48±1.53)U,lower than(32.21±1.47)U of the control group,the difference was statistically significant(P<0.05).Conclusion EECP therapy combined with trimetazidine can effectively improve cardiac function and microcirculation function and enhance clinical efficacy in CHD patients after stenting.
作者 时红宝 SHI Hongbao(Department of Cardiology,Heze Mudan District Central Hospital,Heze Shandong,274000,China)
出处 《反射疗法与康复医学》 2023年第7期144-146,共3页 Reflexology And Rehabilitation Medicine
关键词 冠心病 支架手术 增强型体外反搏 曲美他嗪 心功能 微循环功能 Coronary heart disease Stent surgery Enhanced external counterpulsation Trimetazidine Cardiac function Microcirculation function
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