单孔腹腔镜囊肿剥除术对巨大卵巢囊肿患者卵巢储备功能及术后恢复的影响

Effect of Single Port Laparoscopic Cystectomy on Ovarian Reserve Function and Postoperative Recovery in Patients with Giant Ovarian Cysts

目的分析单孔腹腔镜囊肿剥除术在巨大卵巢囊肿(OC)患者中的应用效果.方法选取2020年3月—2022年3月我院收治的84例巨大OC患者,按随机数字表法分为两组,每组42例.对照组行传统多孔腹腔镜囊肿剥除术,观察组行单孔腹腔镜囊肿剥除术,均观察至术后1个月.对比两组的手术相关指标、术后恢复情况、卵巢储备功能及并发症发生情况.结果观察组的术中出血量为(34.21±2.04)mL,少于对照组的(40.53±2.69)mL,手术时间、住院时间、肠鸣音恢复时间、排气时间、首次排便时间分别为(60.31±2.69)min、(4.21±0.89)d、(9.31±1.26)h、(11.31±2.50)h、(11.19±2.64)h,均短于对照组的(69.26±2.87)min、(5.59±1.26)d、(12.28±2.03)h、(15.69±3.15)h、(16.37±3.26)h,组间差异有统计学意义(P<0.05).术后1个月,观察组的抗苗勒氏管激素水平高于对照组,窦卵泡数多于对照组,卵泡刺激素及促黄体生成素水平均低于对照组,组间差异有统计学意义(P<0.05).两组的并发症发生率比较,差异无统计学意义(P>0.05).结论单孔腹腔镜囊肿剥除术治疗巨大OC的效果理想,能减少术中出血量,缩短术式操作时间,促进术后恢复,且对患者卵巢储备功能影响较小,无严重并发症,临床应用价值较高,可进行大力推行.

Objective To analyze the effect of single port laparoscopic cystectomy in patients with giant ovarian cyst(OC).Methods 84 patients with giant OC admitted to our hospital from March 2020 to March 2022 were selected and were divided into two groups according to random number table method,with 42 cases in each group.The control group received traditional multi hole laparoscopic cystectomy,and the observation group received single port laparoscopic cystectomy.Both groups were observed to 1 month after surgery.The operation related indexes,postoperative recovery,ovarian reserve function and complications were compared between the two groups.Results The intraoperative blood loss in the observation group was(34.21±2.04)mL,less than(40.53±2.69)mL in the control group,the operation time,hospitalization time,bowel sound recovery time,exhaust time and first defecation time were(60.31±2.69)min,(4.21±0.89)d,(9.31±1.26)h,(11.31±2.50)h,(11.19±2.64)h,respectively,which were shorter than(69.26±2.87)min,(5.59±1.26)d,(12.28±2.03)h,(15.69±3.15)h,(16.37±3.26)h in the control group,and the differences between the groups were statistically significant(P<0.05).1 month after surgery,the levels of anti-Mullerian hormone in the observation group was higher than in the control group,the antral follicle count was more than that in the control group,while the levels of follicle stimulating hormone and luteinizing hormone were lower than those in the control group,the differences between the groups were statistically significant(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Single port laparoscopic cystectomy has ideal effect in the treatment of giant OC,which can reduce intraoperative blood loss,shorten operation time and promote postoperative recovery.Besides,it has little effect on the ovarian reserve function of patients and no serious complications.Therefore,it has high clinical application value and can be implemented vigorously.