心脏康复治疗对老年慢性心力衰竭患者心功能及神经内分泌因子的影响

Effects of Cardiac Rehabilitation on Cardiac Function and Neuroendocrine Factors in Elderly Patients with Chronic Heart Failure

目的探讨心脏康复治疗在老年慢性心力衰竭(CHF)患者中的应用效果.方法选取2020年7月—2021年12月本院收治的84例老年CHF患者,按随机数字表法分为两组,每组42例.对照组采用常规治疗,观察组在此基础上采用心脏康复治疗,均持续6个月.对比两组的心功能指标、神经内分泌因子水平及生存质量.结果治疗后,观察组的左室射血分数为(51.23±4.72)%,高于对照组的(46.19±4.54)%,左室舒张末期内径、左室收缩末期内径分别为(50.35±5.80)mm、(43.53±5.16)mm,均短于对照组的(57.66±6.27)mm、(49.69±4.98)mm,组间差异有统计学意义(P<0.05).治疗后,观察组的血管紧张素、N末端脑钠肽前体、醛固酮水平均低于对照组,组间差异有统计学意义(P<0.05).治疗后,观察组的明尼苏达心力衰竭生命质量量表评分为(26.63±4.77)分,低于对照组的(31.25±5.10)分,差异有统计学意义(P<0.05).结论老年CHF患者采用心脏康复治疗的效果显著,能改善心功能指标,降低神经内分泌因子水平,提高其生存质量,值得临床推广使用.

Objective To investigate the effect of cardiac rehabilitation in elderly patients with chronic heart failure(CHF).Methods 84 elderly patients with CHF admitted to the hospital from July 2020 to December 2021 were selected and were divided into two groups according to random number table method,with 42 cases in each group.The control group received conventional treatment,and the observation group received cardiac rehabilitation on this basis.Both groups lasted for 6 months.The cardiac function indexes,neuroendocrine factors and quality of life of the two groups were compared.Results After treatment,the left ventricular ejection fraction of the observation group was(51.23±4.72)%,which was higher than(46.19±4.54)%of the control group,the left ventricular end-diastolic diameter and the left ventricular end-systolic diameter were(50.35±5.80)mm and(43.53±5.16)mm,respectively,lower than(57.66±6.27)mm and(49.69±4.98)mm of the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the levels of angiotensin,N-terminal brain natriuretic peptide precursor and aldosterone in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the Minnesota living with heart failure questionnaire score in the observation group was(26.63±4.77)points,which was lower than(31.25±5.10)points in the control group,the difference was statistically significant(P<0.05).Conclusion The effect of cardiac rehabilitation is significant in elderly patients with CHF,which can improve the cardiac function index,reduce the level of neuroendocrine factors and improve the quality of life.It is worthy of clinical application.