神经康复治疗对脑梗死急性期患者脑血流动力学及神经功能的影响

Effects of Neurorehabilitation Treatment on Cerebral Hemodynamics and Neurological Function in Patients with Cerebral Infarction during the Acute Phase

目的探析神经康复治疗对脑梗死急性期患者脑血流动力学及神经功能的影响.方法选取2019年1月—2021年12月于本院接受诊治的120例脑梗死急性期患者为研究对象,采用随机数字表法分为对照组与观察组,各60例.两组患者均接受溶栓治疗,在此基础上,对照组患者接受常规对症治疗,观察组患者在对照组基础上联合神经康复治疗.对两组患者的临床疗效、神经功能、脑血流动力学指标进行比较.结果观察组患者总有效率高于对照组,差异有统计学意义(P<0.05).观察组患者治疗后大脑中动脉平均流速、收缩峰流速均快于对照组,组间差异有统计学意义(P<0.05).观察组患者治疗后美国国立卫生研究院卒中量表评分、血清S100B蛋白均低于对照组,脑源性神经营养因子高于对照组,组间差异有统计学意义(P<0.05).结论临床针对脑梗死急性期患者在常规对症治疗基础上实施神经康复治疗,对于患者病情控制和远期预后均具有积极影响,能够更好地保障患者的生命健康及顺利回归到正常生活.

Objective To explore the effect of neurorehabilitation treatment on cerebral hemodynamics and neurological function in patients with cerebral infarction during the acute phase.Methods 120 patients with cerebral infarction during the acute phase who received diagnosis and treatment in the hospital from January 2019 to December 2021 were selected as the research objects,and divided into a control group and an observation group by random number table method,with 60 cases in each group.Both groups of patients received thrombolytic therapy.On this basis,the patients in the control group received conventional symptomatic treatment,while the patients in the observation group received neurorehabilitation treatment on the basis of the control group.The clinical efficacy,neurological function and cerebral hemodynamic indexes of the two groups were compared.Results The total effective rate of patients in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the mean velocity and systolic peak flow velocity of the middle cerebral artery in the observation group were faster than those in the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the National Institute of Health stroke scale score and serum S100B protein in the observation group were lower than those in the control group,the brain-derived neurotrophic factor was higher than that of the control group,and the differences between the groups were statistically significant(P<0.05).Conclusion Clinically,neurorehabilitation treatment based on conventional symptomatic treatment for patients with cerebral infarction during the acute phase has a positive impact on the patient's condition control and long-term prognosis,and can better protect the patient's life and health and smoothly return to normal life.