血必净结合物理康复训练对老年肺部感染患者呼吸功能和炎症反应的影响

Effect of Xuebijing Combined with Physical Rehabilitation Training on Respiratory Function and Inflammatory Response in Elderly Patients with Pulmonary Infection

目的探讨血必净结合物理康复训练对老年肺部感染患者呼吸功能和炎症反应的影响.方法选择2020年1月—2021年12月本院收治的老年肺部感染患者92例,随机分为两组,各46例.对照组采用常规西药治疗,观察组在对照组基础上采用血必净结合物理康复训练干预.比较两组临床疗效,检测治疗前和治疗14 d后呼吸力学指标以评估患者呼吸功能,另检测C反应蛋白(CRP)、降钙素原(PCT)、白细胞介素(IL)-6水平以评估炎症反应.结果观察组治疗总有效率95.65%高于对照组的80.43%,差异有统计学意义(P<0.05).治疗14 d后,观察组肺动态顺应性(36.84±6.12)mL/cmH_(2)O高于对照组,气道阻力(16.56±3.15)cmH_(2)O/(L·s)、响应频率(18.91±3.12)Hz、气道平均压(6.58±0.75)cmH_(2)O均低于对照组,组间差异有统计学意义(P<0.05).治疗14 d后,观察组CRP水平(9.62±2.74)mg/L、PCT水平(1.03±0.27)ng/mL、IL-6水平(20.56±5.56)pg/mL均低于对照组,组间差异有统计学意义(P<0.05).结论对老年肺部感染患者采用血必净结合物理康复训练能提高临床疗效,改善患者呼吸功能,减轻炎症反应.

Objective To investigate the effect of Xuebijing combined with physical rehabilitation training on respiratory function and inflammatory response in elderly patients with pulmonary infection.Methods A total of 92 elderly patients with pulmonary infection admitted to the hospital from January 2020 to December 2021 were selected and randomly divided into two groups,with 46 cases in each group.The control group was treated with conventional western medicine treatment,and the observation group was treated with Xuebijing combined with physical rehabilitation training.The clinical efficacy of the two groups was compared,respiratory mechanics indexes before and after 14 d of treatment were detected to evaluate the respiratory function of patients,and C-reactive protein(CRP),procalcitonin(PCT)and interleukin(IL-6)were also detected to evaluate the inflammatory response.Results The total effective rate of treatment 95.65%of observation group was higher than 80.43%of control group,and the difference was statistically significant(P<0.05).After 14 d of treatment,the pulmonary dynamic compliance(36.84±6.12)mL/cmH_(2)O of the observation group was higher than that of the control group,airway resistance(16.56±3.15)cmH_(2)O/(L·s),response frequency(18.91±3.12)Hz and airway mean pressure(6.58±0.75)cmH_(2)O were lower than those of the control group,and the differences between the groups were statistically significant(P<0.05).After 14 d of treatment,the CRP level(9.62±2.74)mg/L,PCT level(1.03±0.27)ng/mL and IL-6 level(20.56±5.56)pg/mL in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).Conclusion Xuebijing combined with physical rehabilitation training for elderly patients with pulmonary infection can improve clinical efficacy,improve respiratory function and reduce inflammation.