心脏康复对慢性心力衰竭患者心功能和脑钠肽的影响

Effects of Cardiac Rehabilitation on Cardiac Function and Brain Natriuretic Peptide in Patients with Chronic Heart Failure

目的探讨心脏康复对慢性心力衰竭患者心功能、运动能力及脑钠肽的影响.方法选取2020年1月—2021年3月我院收治的74例慢性心力衰竭患者为研究对象,按照随机数字表法分为研究组与对照组,各37例.研究组采用系统心脏康复治疗,对照组采用常规治疗.观察两组的治疗效果,并比较两组干预前后的左室射血分数(LVEF)、左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、6 min步行试验(6MWT)及血清N末端B型脑钠肽原(NT-proBNP)水平.结果研究组的治疗总有效率为89.19%,高于对照组的70.27%,差异有统计学意义(P<0.05).干预后,研究组的LVEF高于对照组,LVEDV、LVESV、NT-proBNP均低于对照组,6MWT长于对照组,组间差异有统计学意义(P<0.05).结论心脏康复可改善慢性心力衰竭患者的心功能,提高其运动能力,降低脑钠肽水平,对改善患者预后具有积极作用,值得临床推广应用.

Objective To investigate the effects of cardiac rehabilitation on cardiac function,exercise ability and brain natriuretic peptide in patients with chronic heart failure.Methods A total of 74 patients with chronic heart failure admitted to our hospital from January 2020 to March 2021 were selected as the research objects,and were divided into a study group and a control group by random number table method,with 37 cases in each group.The study group used systematic cardiac rehabilitation treatment,and the control group used routine treatment.The therapeutic effect of the two groups was observed,and the left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),6 min walking test(6MWT)and serum N-terminal B-type brain natriuretic peptide(NT-probNP)level were compared between the two groups before and after intervention.Results The total effective rate of the study group was 89.19%,which was higher than 70.27%of the control group,the difference was statistically significant(P<0.05).After intervention,the LVEF of the study group was higher than that of the control group,LVEDV,LVESV and NT-probNP were lower than those of the control group,6MWT was longer than that of the control group,the differences between the groups were statistically significant(P<0.05).Conclusion Cardiac rehabilitation can improve the cardiac function of patients with chronic heart failure,improve their exercise ability,reduce the level of brain natriuretic peptide,has a positive effect on improving the prognosis of patients and is worthy of clinical application.