茶碱缓释片联合呼吸功能锻炼治疗慢性阻塞性肺疾病的临床效果分析

Analysis of the Effect of Theophylline Sustained-Release Tablets Combined with Respiratory Function Exercise in the Treatment of Chronic Obstructive Pulmonary Disease

目的探讨慢性阻塞性肺疾病患者采用茶碱缓释片联合呼吸功能锻炼治疗的临床效果.方法选择该院2019年6月—2020年6月收治的慢性阻塞性肺疾病患者98例为研究对象,以随机数表法分为两组.对照组(n=49)采用茶碱缓释片治疗,观察组(n=49)采用茶碱缓释片联合呼吸功能锻炼治疗.对比两组临床疗效,检测两组患者治疗前后肺功能指标,包括用力肺活量、第1秒用力呼气容积、呼气峰流速,并采用慢性阻塞性肺疾病评估测试评价两组患者治疗前后的生活质量.结果观察组总有效率为95.92%,高于对照组的83.67%,差异有统计学意义(P<0.05).治疗后,观察组用力肺活量、第1秒用力呼气容积、呼气峰流速分别为(1.97±0.20)L、(1.88±0.31)L、(227.45±21.53)L/min,均优于对照组.主观指标、耐受力指标评分分别为(8.63±2.40)分、(3.31±0.82)分,均高于对照组,差异有统计学意义(P<0.05).结论临床对慢性阻塞性肺疾病患者采用茶碱缓释片联合呼吸功能锻炼治疗,可提高疗效,改善患者的肺功能及生活质量.

Objective To investigate the clinical effect of theophylline sustained-release tablets combined with respirato ry function exercise in patients with chronic obstructive pulmonary disease.Methods A total of 98 patients with chronic obstructive pulmonary disease admitted to the hospital from June 2019 to June 2020 were selected as the research objects,and divided into two groups by random number table method.The control group(n=49)was treated with theophylline sustained-release tablets,and the observation group(n=49)was treated with theophylline sustained-release tablets combined with respiratory function exercise.The clinical efficacy of the two groups was compared,pulmonary function indicators in the two groups before and after treatment were detected,including forced vital capacity,forced expiratory volume in one second,peak expiratory flow rate,and the chronic obstructive pulmonary disease assessment test was used to evaluate the quality of life of the two groups of patients before and after treatment.Results The total effective rate in the observation group was 95.92%,which was higher than 83.67%in the control group,and the difference was statistically significant(P<0.05).After treatment,the forced vital capacity,forced expiratory volume in one second and peak expiratory flow rate of observation group were(1.97±0.20)L,(1.88±0.31)L,(227.45±21.53)L/min,respectively,which were better than those of the control group.The scores of subjective index and tolerance index were(8.63±2.40)points and(3.31±0.82)points,respectively,which were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Clinical use of theophylline sustained-release tablets combined with respiratory function exercise for patients with chronic obstructive pulmonary disease can improve the curative effect and improve the lung function and quality of life of patients.