高频重复经颅磁刺激治疗对慢性偏头痛患者疼痛程度、睡眠质量及生活质量的影响

The Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation Treatment on Pain Degree, Sleep Quality and Quality of Life in Patients with Chronic Migraine

目的探讨慢性偏头痛患者采用高频重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)治疗对其疼痛程度、睡眠质量及生活质量的影响.方法选取2020年1月—2021年1月在该院接受治疗的90例慢性偏头痛患者为研究对象,根据随机数字表法分为观察组(n=45)与对照组(n=45).对照组采用假刺激治疗,观察组采用高频rTMS治疗.对两组治疗前后的疼痛程度、睡眠质量及生活质量进行比较.结果两组治疗后的疼痛视觉模拟评分(visual analogue scale,VAS)均较各组治疗前明显下降,且观察组VAS评分较对照组明显更低,组间差异有统计学意义(P<0.05).两组治疗后的匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)评分均明显低于各组治疗前,且观察组PSQI评分明显低于对照组,组间差异有统计学意义(P<0.05).两组治疗后的各项偏头痛特异性生活质量问卷(V2.1)评分均较各组治疗前明显下降,且观察组的情感功能、功能限制、功能丧失评分均较对照组明显更低,组间差异有统计学意义(P<0.05).结论临床上采用高频rTMS治疗慢性偏头痛患者,可有效降低其疼痛程度,改善睡眠质量,提高生活质量.

Objective To explore the effects of high-frequency repetitive transcranial magnetic stimulation(rTMS)treatment in patients with chronic migraine on their pain degree,sleep quality and quality of life.Methods 90 patients with chronic migraine who were treated in the hospital from January 2020 to January 2021 were selected as the research objects,and were divided into an observation group(n=45)and a control group(n=45)according to the random number table method.The control group was treated with false stimulation,and the observation group was treated with high-frequency rTMS.The pain degree,sleep quality and quality of life before and after treatment were compared between the two groups.Results The pain visual analogue scale(VAS)of the two groups after treatment was significantly lower than that of each group before treatment,and the VAS score of the observation group was significantly lower than that of the control group,and the difference between the groups was statistically significant(P<0.05).The Pittsburgh sleep quality index(PSQI)scores of the two groups after treatment were significantly lower than those of each group before treatment,and the PSQI score of the observation group was significantly lower than that of the control group,and the difference between the groups was statistically significant(P<0.05).The Migraine-Specific Quality-of-Life Questionnaire(V2.1)scores of the two groups after treatment were significantly lower than those of each group before treatment,and the scores of emotional function,functional limitation,and loss of function of the observation group were significantly lower than those of the control group,and the difference between the groups was statistically significant(P<0.05).Conclusion Clinically,high-frequency rTMS is used to treat patients with chronic migraine,which can effectively reduce their pain,improve the quality of sleep,and improve the quality of life.