摘要
Introduction Lues maligna is an uncommon,severe form of secondary syphilis.Most cases are linked to poorly controlled human immunodeficiency virus(HIV)infection with cluster of differentiation 4 lymphocyte(CD4)counts between 100 and 350,1 and immune reconstitution inflammatory syndrome has been reported to increase the risk of lues maligna.2 Here we describe an uncommon case of lues maligna complicated by syphilitic hepatitis in a patient with virologically suppressed and immune-reconstituted HIV infection during the brief period when he had stopped his medications,and review the literature about this rare and potentially fatal form of syphilis.