摘要
肥胖已经成为日益严重的社会公共健康问题.既往研究发现,肥胖是心血管疾病发生的独立危险因素之一,但在罹患心血管疾病人群中,肥胖患者的预后较无肥胖患者好.肥胖在健康与疾病的不同背景下,发挥了截然相反的作用,这种现象被称为'肥胖悖论'.本文以心力衰竭作为疾病背景,在梳理既往研究和文献基础上,对这一现象进行讨论.
Obesity has become increasingly serious social public health problems now.Previous studies found that obesity is one of the independent risk factors for cardiovascular disease,but the prognosis of obese patients is better than that of non-obese patients.Obesity plays an opposite role in different backgrounds of health and disease,which is called'obesity paradox'.This article will take heart failure as disease background to discuss the phenomenon on the basis of previous studies and literature.
作者
薛彦博
马琼
马爱群
Xue Yanbo;Ma Qiong;Ma Aiqun(Department of Cardiovascular Medicine,First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Key Laboratory of Molecular Cardiology,Key Laboratory of Environment and Genes Related to Diseases,Ministry of Education,Xi'an 710061,China)
基金
国家科技惠民计划(2012GS610101)
国家重点研发计划(2017YFC1308302).
关键词
心力衰竭
肥胖悖论
预后
Heart failure
Obesity paradox
Prognosis
