低浓度阿托品控制不同程度近视疗效分析

目的 观察分析低浓度阿托品在延缓青少年不同程度近视中的作用.方法 将30例(60只眼)中低度近视患者随机分成治疗组15例(30只眼)和对照组15例(30只眼);同样将30例60只眼的高度近视患者随机分成治疗组15例(30只眼)和对照组15例(30只眼).治疗组每晚双眼滴0.01%阿托品滴眼液,白天佩戴框架眼镜;对照组仅常规佩戴框架眼镜.随访观察1年,分析患者屈光度及眼轴长度变化评价低浓度阿托品在控制不同程度近视进展中的疗效.结果 观察1年后,各组屈光度变化及眼轴长度变化差值分析结果如下:在中低度近视患者中,治疗组与对照组比较差异有统计学意义(P<0.001);在高度近视患者中,治疗组与对照组比较差异有统计学意义(P<0.001).结论 低浓度阿托品能安全有效控制中低度近视患者和高度近视患者近视的进展.

Objective To investigate the efficacy of low concentration atropine on myopic juvenile patients with different diopter.Methods 30 subjects(60 eyes)with low and moderate myopia were randomized divided into treatment group(15 cases,30 eyes)and control group(15 cases,30 eyes).30 subjects(60 eyes)with high myopia were randomized divided into treatment group(15 cases,30 eyes)and control group(15 cases,30 eyes)as well.The treatment group was treated with atropine eye drops(0.01%)every evening in both eyes and weared spectacles daytime.The control group was treated with spectacles.After 1 year follow-up,the changes of diopter and ocular axial length of patients were statistically analyzed.Results After 1 year,the results of diopter and ocular axial length changes among the groups were as follows:among patients with low and moderate myopia,the treatment group compared with the control group had statistical significance(P<0.001);among patients with high myopia,the treatment group compared with the control group had statistical significance(P<0.001).Conclusion Atropine 0.01%was effective and safe for reducing the progression of juvenile myopia.