摘要
炎症性肠病(IBD)的发病率在世界范围内持续上升,其发病与饮食方式西方化密切相关.近年来研究显示饮食是肠道微生态最重要的影响因素之一,肠道微生态在IBD的发病中起着关键作用,饮食可能通过肠道微生态发挥作用.现就IBD营养相关因素、肠道微生态变化在IBD发生发展中的作用及机制作简要论述.
The incidence of inflammatory bowel disease(IBD)is rising worldwide,and its onset is closely related to the westernization of dietary patterns.In recent years,studies have shown that diet is one of the most important factors influencing gut microbiota,and gut microbiota plays a key role in the pathogenesis of IBD,then diet may play a role through altering gut microbiota.This paper briefly reviews the role and mechanism of IBD-related nutrition factors and intestinal microbial changes in the development of IBD.
作者
孙丽娟
聂勇战
Sun Lijuan;Nie Yongzhan(State Key Laboratory of Cancer Biology,National Clinical Research Center for Digestive Diseases,Xijing Hospital of Digestive Diseases,Air Force Medical University,Xi′an 710032,China;Department of Clinical Nutrition,Xijing Hospital,Air Force Medical University,Xi′an 710032,China)
出处
《中华炎性肠病杂志(中英文)》
2019年第3期217-221,共5页
Chinese Journal of Inflammatory Bowel Diseases
基金
国家自然科学基金(81730016).
关键词
炎症性肠病
营养治疗
肠道微生态
肠黏膜屏障
免疫功能
Inflammatory bowel disease
Nutritional therapy
Gut microbiota
Intestinal barrier
Immune function