期刊文献+

溃疡性结肠炎合并巨细胞病毒感染诊断的研究进展 被引量:1

原文传递
导出
摘要 溃疡性结肠炎(ulcerative colitis, UC)患者是发生机会性感染的高危人群,其中巨细胞病毒(cytomegalovirus, CMV)感染较为常见[1,2].CMV感染可导致UC病情加重,常规药物疗效欠佳.检测CMV感染的方法较多,但在肠道CMV感染的诊断价值有待提高.本文对UC合并CMV感染进行综述. 一、UC合并CMV感染的流行病学 CMV属人类疱疹病毒p亚科,为线性双链DNA病毒.CMV感染在人群中常见,血清学抗体阳性率高达40% ~100%[3].初次感染CMV后,病毒多潜伏于白细胞和内皮细胞内,当机体的免疫功能减退时,可再被激活引起全身各系统的感染[3].UC患者感染的CMV风险高于普通人群,且与UC疾病严重程度相关.欧美国家UC人群CMV感染率约为10% ~ 38%,亚洲 UC人群 CMV感染率为4.5% ~ 50%[4].
出处 《中华炎性肠病杂志(中英文)》 2018年第1期61-64,共4页 Chinese Journal of Inflammatory Bowel Diseases
  • 相关文献

参考文献6

二级参考文献141

  • 1Hideyuki Suzuki,Jun Kato,Motoaki Kuriyama,Sakiko Hiraoka,Kenji Kuwaki,Kazuhide Yamamoto.Specific endoscopic features of ulcerative colitis complicated by cytomegalovirus infection[J].World Journal of Gastroenterology,2010,16(10):1245-1251. 被引量:19
  • 2Pilar López-Serrano,Jose Lázaro Pérez-Calle,Maria Dolores Sánchez-Tembleque.Hepatitis B and inflammatory bowel disease: Role of antiviral prophylaxis[J].World Journal of Gastroenterology,2013,19(9):1342-1348. 被引量:12
  • 3Elena Garrido,Elisa Carrera,Rebeca Manzano,Antonio Lopez-Sanroman.Clinical significance of cytomegalovirus infection in patients with inflammatory bowel disease[J].World Journal of Gastroenterology,2013,19(1):17-25. 被引量:7
  • 4Damian Casadesus,Tatsuo Tani,Toshifumi Wakai,Satoshi Maruyama,Tsuneo iiai,Haruhiko Okamoto,Katsuyoshi Hatakeyama.Possible role of human cytomegalovirus in pouchitis after proctocolectomy with ileal pouch-anal anastomosis in patients with ulcerative colitis[J].World Journal of Gastroenterology,2007,13(7):1085-1089. 被引量:4
  • 5You DM, Johnson MD. Cytomegalovirus infection and thegastrointestinal tract. Curr Gastroenterol Rep 2012; 14: 334-342#[PMID: 22588614 DOI: 10.1007/s11894-012-0266-4].
  • 6Goodman AL, Murray CD, Watkins J, Griffiths PD, WebsterDP. CMV in the gut: a critical review of CMV detection in theimmunocompetent host with colitis. Eur J Clin Microbiol InfectDis 2015; 34: 13-18 [PMID: 25097085 DOI: 10.1007/s10096-014-2212-x].
  • 7Galiatsatos P, Shrier I, Lamoureux E, Szilagyi A. Meta-analysisof outcome of cytomegalovirus colitis in immunocompetent hosts.Dig Dis Sci 2005; 50: 609-616 [PMID: 15844689].
  • 8Seo TH, Kim JH, Ko SY, Hong SN, Lee SY, Sung IK, Park HS,Shim CS, Han HS. Cytomegalovirus colitis in immunocompetentpatients: a clinical and endoscopic study. Hepatogastroenterology2012; 59: 2137-2141 [PMID: 23435132 DOI: 10.5754/hge10825].
  • 9Ko JH, Peck KR, Lee WJ, Lee JY, Cho SY, Ha YE, Kang CI,Chung DR, Kim YH, Lee NY, Kim KM, Song JH. Clinicalpresentation and risk factors for cytomegalovirus colitis inimmunocompetent adult patients. Clin Infect Dis 2015; 60: e20-e26[PMID: 25452594 DOI: 10.1093/cid/ciu969].
  • 10Pillet S, Roblin X, Cornillon J, Mariat C, Pozzetto B. Quantificationof cytomegalovirus viral load. Expert Rev Anti Infect Ther2014; 12: 193-210 [PMID: 24341395 DOI: 10.1586/14787210.2014.870887].

共引文献111

同被引文献2

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部