妊娠高血压疾病患者分娩前后血清C反应蛋白和褪黑素水平的变化

The change of serum C reactive protein and melatonin levels in patients with hypertensive disorder of pregnancy before and after delivery

目的:探讨妊娠高血压疾病患者分娩后血清 C-反应蛋白和褪黑素水平,分娩前后进行对比,进一步研究CRP及MT在妊娠高血压疾病发生发展中所起的作用。方法选取轻度子痫前期患者30例,重度子痫前期患者60例,检测其分娩前后血清CRP值及MT值。结果轻度子痫前期及重度子痫前期患者产后第一天的CRP均值明显高于产前,产后第五天的CRP均值明显低于产前。产前与产后第一天,产前与产后第五天的差别均有统计学意义(P<0.05)。轻度子痫前期及重度子痫前期患者产后第一天及第五天的血清MT均值高于产前,差异具有显著性意义(P<0.05)。结论子痫前期患者产后随病情减轻,CRP的浓度水平逐渐下降,褪黑素的浓度水平逐渐上升,可通过检测血浆CRP及MT水平的高低用于评估病情的严重程度。

Objective Study on hypertension patients after the birth of the expression of serum C-reactive protein and melatonin levels were compared before and after pregnancy,childbirth,the further study of CRP and MT in hypertensive disorder complicating pregnancy occurred in the role of the development.Methods Select 30 cases of patients with mild preeclampsia,60 cases of severe preeclampsia patients,serum CRP value and MT value before and after delivery.Results Mild pre-eclampsia and severe preeclampsia patients first day had a higher average CRP than prenatal,postpartum fifth days had a lower average CRP than prenatal.The first days of prenatal and postnatal,prenatal and postnatal day fifth there are statistically significant differences.Conclusions Postpartum preeclampsia patients with ease,the concentration level of CRP decreased gradually,the level of melatonin concentration gradually increased,the plasma CRP and MT levels for assessment of severity of disease.