C反应蛋白与脂肪酶对早期重症急性胰腺炎评估的意义

C reactive protein and lipase on the significance of the evaluation of early severe acute pancreatitis

目的:探究C反应蛋白与脂肪酶在重症急性胰腺炎早期评估中的临床价值与意义。方法研究对象选取为2010年1月-2014年1月之间我院收治的243例重症急性胰腺炎患者,以此作为观察组,选取同期的422例健康体检者作为对照组,采用免疫比浊法进行两组患者C反应蛋白和脂肪酶的检测,并对检测结果进行对比分析。结果观察组患者的C反应蛋白和脂肪酶水平显著高于对照组,差异具有统计学意义(P<0.05);在敏感性和特异性的检测试验中,C反应蛋白和脂肪酶联合检测的敏感性和特异性分别为81.89%(199/243)和100.00%(243/243),显著高于两者单独检测,差异具有统计学意义(P<0.05)。结论 C反应蛋白和脂肪酶有助于重症急性胰腺炎患者的早期诊断,联合检测更能够提高敏感性和特异性,值得在临床上推广和应用。

Objective To explore the clinical value and significance of C reactive protein and lipase in the early assessment of severe acute pancreatitis.Methods The study selected 243 cases of patients with severe acute pancreatitis is between January 2010 January 2014 in our hospital,so as the observation group,422 healthy persons were selected as control group,detected by immunoturbidimetry in two patients of C reactive protein and lipase,and compared the test results analysis.Results In the observation of C reactive protein and lipase levels were significantly higher than that of control group,the difference was statistically significant(P<0.05);in the test sensitivity and specificity,C reactive protein and lipase joint detection sensitivity and specificity were 81.89%(199/243)and 100%(243/243),significantly higher than that of the two separate detection,the difference was statistically significant(P<0.05).Conclusion The early diagnosis of C reactive protein and lipase could help patients with severe acute pancreatitis,joint detection can improve the sensitivity and specificity,is worthy of clinical popularization and application.