垂体后叶素联合酚妥拉明治疗支气管扩张大咯血的效果研究

Study on the Effect of Pituitrin and Phentolamine in Treatment of Bronchiectasis with Massive Hemoptysis

目的:观察垂体后叶素与酚妥拉明联合治疗支气管扩张大咯血患者临床方法与效果。方法选取我院2014年10月~2015年12月收治的支气管扩张大咯血患者共70例,随机均分为对照组与治疗组两组,对照组患者于基础治疗联合垂体后叶素治疗,治疗组在对照组基础上采用酚妥拉明强化治疗方案。结果经不同药物方案治疗后,治疗组35例患者中,显效患者23例、有效患者10例、无效患者2例,临床治疗总有效率94.3%,显著高于对照组(P<0.05);不良反应发生率对比,治疗组35例患者治疗期间出现头痛患者1例、胸闷患者1例、腹痛0例、恶心呕吐2例,整体不良反应发生率11.4%,显著低于对照组(P<0.05)。结论垂体后叶素与酚妥拉明联合治疗支气管扩张大咯血患者,具有着确切的临床疗效,且患者治疗期间不良反应发生率较低。

Objective To observe the pituitrin and phentolamine combined treatment of bronchiectasis hemoptysis patients clinical methods and effects.Methods From October 2014 to December 2015 were a total of 70 patients with bronchiectasis big haemoptysis,comprehensive curative effect observation contrast 2 groups of patients and adverse reactions occur.Results After treatment with different drugs scheme,the treatment group of 35 cases,23 cases of patients were markedly improved,2 cases of 10 patients with valid,was 94.3%,significantly higher than that of control group(P<0.05);observation group of 35 cases of patients during treatment in patients with headache in 1 case,the overall incidence of adverse reactions to 11.4%,significantly lower than that of control group(P<0.05).Conclusion Pituitrin and phentolamine combined treatment of bronchiectasis hemoptysis patients,of adverse reactions.