胆囊收缩素与肝内胆管结石的相关性研究

Study on the Relationship between CCK and Intrahepatic Bile Duct Stones

目的 研究胆囊收缩素(CCK)与肝内胆管结石形成的相关性.方法 随机选择肝内胆管结石患者50例为实验组;另外随机选择无肝内胆管结石患者50例作为对照组;术前空腹抽肘前静脉血2 ml;离心后取上清液严格按试剂盒使用说明进行测定.所有数值以(±)表示,两组比较用检验,采用SPSS统计软件处理分析.结果 实验组患者术前血清中的胆囊收缩素水平明显高于对照组,具有统计学意义(<0.05).结论 血浆中的胆囊收缩素水平与肝内胆管结石的形成具有明确的相关性.

Objective To study the cholecystokinin(CCK)and intrahepatic bile duct stone formation relevance.Methods Hepatolithiasis randomly selected 50 patients as experimental group;no additional randomly selected 50 patients with intrahepatic bile duct stones as a control group;preoperative fasting venous blood before pumping 2ml;supernatant after centrifugation strictly according to the kit instructions were measured.All values are expressed with x±s,the two groups using t test using spss statistical software analysis.Results Patients in the experimental group serum cholecystokinin levels were significantly higher,with statistical significance(<0.05).Conclusion CCK levels in plasma and formation of intrahepatic bile duct stones have a clear correlation.