中西医结合治疗乙肝肝硬化临床疗效和安全性评估

Clinical Efficacy and Safety Evaluation of Integrated Traditional Chinese and Western Medicine in Treatment of Hepatitis B Cirrhosis

目的:本研究旨在通过对中西医结合治疗乙肝肝硬化临床疗效和安全性进行评估,明确该病的有效治疗方案,为临床提供依据。方法选择我院2013年3月~2015年3月接收的乙肝肝硬化患者88位,随机分为对照组与观察组,各44例。对照组患者采用常规保肝治疗(口服拉米夫定),观察组在此基础上采用中西医结合治疗。结果治疗后,两组患者病情均得到改善,但观察组病情改善效果显著,观察组患者肝功能及影像学指标明显优于对照组,组间存在明显差异(<0.05);对照组患者的住院时间以及不良反应发生率均明显多于观察组,差异具有统计学意(<0.05)。结论采用中西医结合治疗乙肝肝硬化较传统治疗方法疗效显著,安全性好,能够明显降低患者不良反应发生率,改善患者的生活质量。

Objective To explore the effect of intergrative medicine in caring for patients with Hepatitis B liver cirrhosis.Methods 88 cases of hepatitis B liver cirrhosis from 2014 to 2015 in our hospital were selected as the research obeject,they were randomly divided into control group and study group,the former received usual care(lamivudine),the latter received integative medicine.Results The length of stay,ADR,liver function inidcators and imaging index in the study group was significantly better than control group,the difference between the two groups was significant(<0.05).Conclusion The implementation of the integative medicine has significant effect,it can shorten hospital stay and ADR of Hepatitis B liver cirrhosis and improve the quality of life of patient.