妊娠妇女早晚期血浆纤蛋白原含量变化及探讨

Changes of Plasma Fibrinogen Levels in the Early and Late Stage of Pregnancy

目的:探讨早、晚期妊娠妇女血浆纤维蛋白原(Fbg)在体内的变化及临床意义。方法 CA1500血凝仪检测100例早期妊娠晚妇女和100例晚期妊娠孕妇血浆中的血浆纤蛋白原含量变化,观察早、晚两期之前的数值的变化是升高还是降低,并进行分析比较。结果妊娠晚期组明显高于妊娠早期组,差异有统计学意义(<0.05)。结论妊娠期妇女随着孕期的延长,血浆纤维蛋白原含量也随之升高,有利于止血[1],晚期妊娠孕妇血液处于高凝状态,妊娠晚期后常规检测血浆纤蛋白原对于产程中和产后异常出血、观察孕妇凝血功能情况、预防出血及DIC有着及其重要意义。在妊娠的不同时期,血液的凝血、抗凝和纤溶功能均有明显变化。妊娠期血液呈高凝状态各项凝血功能指标也均有明显的变化,在分娩时易诱发DIC及血栓栓塞性疾病。本文对孕期孕妇分成早、晚两个时期测定其血液中血浆纤蛋白原含量在体内的变化。

Objective To explore,early and late pregnancy women fiber plasma fibrinogen(FBG)in vivo changes and its clinical significance.Methods CA1500 hemagglutination(HA)detector for 100 cases of early pregnancy late women and 100 cases of late pregnancy in maternal plasma plasma fibrin content changes,observation of early and late phase before the numerical changes is higher or lower,compared and analyzed.Results In the late pregnancy group,the difference was statistically significant(<0.05).Conclusion Pregnant women with prolonged pregnancy,plasma fibrinogen content also increased,to stop bleeding[1],late pregnancy blood hypercoagulability,late pregnancy after routine detection of plasma fibrinogen for labor and postpartum hemorrhage,abnormal blood coagulation function,observation of pregnant women and has an important significance in the prevention of hemorrhage and DIC.In different periods of pregnancy,blood coagulation,anticoagulation and fibrinolysis were significantly different.Pregnancy in a hypercoagulable state of the blood coagulation indexes also have obvious changes,induced DIC and thromboembolic disease easily in childbirth.In this paper,the changes of plasma fibrinogen levels in the blood of pregnant women were divided into early and late two stages.