期刊文献+

N0期阴茎癌患者行腹股沟淋巴结清扫的意义

下载PDF
导出
摘要 目的:探讨N0期阴茎癌患者行腹股沟淋巴结清扫的意义。方法回顾性分析本院就诊的149例病理确诊为阴茎鳞状细胞癌患者资料,采用2检验比较分组间复发率。结果阴茎部分切除患者中随访出现14例原发灶复发,N0期患者术后检查确诊出现4例患者原发灶复发并伴有盆腔淋巴结转移,5年复发率达8.0%,未行腹股沟淋巴结清扫术组原发灶复发率为19.2%,两者差异无统计学意(2=2.07,=0.15)。经单因素和多因素Logistic回归分析T分期和病理分型级别越高,越容易复发,清扫组5年生存率和未清扫组5年无进展生存率与未清扫组比较无明显差异。结论阴茎癌患者出现淋巴结转移应积极行淋巴结清扫术,但对于低危(临床分期分级为Tis、Ta、T1G1、表浅型T1G2)阴茎癌患者,由于手术并发症较多且复发病灶可直接转移到盆腔,复发危险度更大,不推荐直接预防性淋巴结清扫。
出处 《医学信息(医学与计算机应用)》 2016年第25期72-74,共3页 Medical Information
  • 相关文献

参考文献1

二级参考文献27

  • 1Horenblas. Lymphadenectomy for squamous cen carcinoma of the penis. Part 1: diagnosis of lymph node metastasis. BJU Int, 2001, 88: 467-472.
  • 2Kroon BK, Horenblas S, Meinhardt W, et al. Dynamic sentinel node biopsy in penile carcinoma: evaluation of 10 years experience. Eur Urol, 2005, 47: 601606.
  • 3Leijte JA, Hughes B, Graafland NM, et al. Two-center evaluation of dynamic sentinel node biopsy for squamous cell carcinoma of the penis. J Clin Oneol, 2009, 27: 3325-3329.
  • 4Leijte JAP, Kroon BK, Valdes Olmos RA, et al. Reliability and safety of current dynamic sentinel node biopsy for penile carcinoma. Eur Urol, 2007, 52: 170-177.
  • 5Leijte JAP, Valdes Olmos RA, Nieweg OE, et al. Anatomic mapping of lylmphatic drainage in penile carcinoma with SPECT-CT: implications for the extent of inguinal lymph node dissection. Eur lJrol, 2008, 54: 885-890.
  • 6Cubanas RM. An approach for the treatment of penile carcinoma. Cancer, 1977, 39: 456-466.
  • 7Martin EW, Jr Mojzisik CM, Hinkle GH Jr, et al Radioimmunoguided surgery using monoclonal antibody. Am J Surg, 1988, 156: 386-392.
  • 8Saha S, Wiese D, Badin D, et al. Technical details of sentinel lymphilode mapping in colorectal cancer and its impact on staging. Ann Surg Oncol, 2000, 7: 82-84.
  • 9Terakawa T, Miyake H, Fujisawa M, et al. Improved sensitivity for detecting micrometastases in pelvic lymph nodes by real-time reverse transcriptase polymerase chain reaction (RT-PCR) compared with conventional RT-PCR in patients with clinically localized prostate cancer undergoing radical prostatectomy. BJU Int, 2009, 103: 1074-1078.
  • 10Murray NP, Reyes E, Fuentealba C, et al. Detection and characteristics of primary circulating prostate cells; association with micrometastasis and implications for surgical treatment of men with prostate cancer. Arch Esp Urol, 2010, 63 : 345-353.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部