摘要
目的:西甲硅油治疗早产儿胃食管返流临床效果观察。方法选择诊断符合胃食管返流40例早产儿,胎龄在29~34w,随机分为两组,对照组和治疗组,每组20例,对照组给予抬高体位、饮食疗法等常规治疗等处理,治疗组在此基础上给予西甲硅油治疗,观察两组患儿胃食管返流缓解情况﹑达到全肠道内喂养时间及体重开始增长时间,并观察有无药物不良反应。结果使用西甲硅油后可更快缓解胃食管返流,使患儿更快达到全肠道内喂养,体重尽快出现增长,差异有统计学意义(P<0.05),并且未发现不良反应的发生。结论西甲硅油治疗早产儿胃食管返流的临床疗效显著。
Objective To observe the clinical ef icacy of simethicon for treating gastroesophageal reflux diseases(GERD)with feeding intolerance.Methods Selected FI diagnosis,gestational age of 40 premature infants in 29~34 weeks,divided them into 2 groups randomly,the control group and the treatment group,each group of 20 cases.The control group was treated with conventional therapy such as elevated position die etc,on this basis,the treatment group was treated with simethicon.Then observed the two groups of children with feeding intolerance remission,the increasing of body weight and the length of hospital stay,at the same time,observed whether there was adverse drug reaction.Results After using simethicone,it could reduce gastric retention,vomiting and abdominal distension earlierly,and enabled children toreach ful enteral feeding faster,thus appeared faster growth,the body weight at discharge was greater than the control group.It also could shorten the time of hospitalization.The dif erence was statistical y significant(<0.05).There was no adverse drug reaction.Conclusion The clinical ef ect of simethicon for treating premature infants with GERD was significant.
作者
郭琳
GUO Lin(Department of Neonatology,The Affiliated Hospital of Luzhou Medical College,Luzhou 646000,Sichuan,China)
