头孢曲松试敏液浓度对皮试结果的影响

Effect of Ceftriaxone Sensitive Test Solution Concentration on the Skin Test Results

目的:通过不同浓度试敏液对患者的测试,观察能否降低皮试的假阴性。方法选取无青霉素严重过敏史及头孢曲松无过敏史的患者400例,分别用浓度为1250 ug/mL和500 ug/mL的头孢曲松钠原液做皮试。用药以任一浓度皮试液皮试结果阴性为准,观察统计假阴性结果例数。结果浓度为500 ug/mL试敏液做皮试发现假阴性14例,所致过敏反应发生率7%;浓度为1250 ug/mL皮试发生假阴性结果9例,所致过敏反应率4.5%。两者相比较2=1.15,>0.05。结论不能证明提高头孢曲松钠试敏液浓度可降低皮试假阴性结果引起的过敏反应发生率。

Objective Through the dif erent concentration of test sensitivity test for patients,observe whether it can reduce false positive skin test.Methods Select without severe al ergies and ceftriaxone penicil in al ergy history of 400 cases of patients,respectively,with concentration of 1250 ug/ml and 500 ug/ml of ceftriaxone sodium concentrate to do skin test.Drugs to any concentration of skin test skin test result is negative,observation statistics were false negative results.Results The concentration of 500 ug/ml try sensitive liquid found 14 of the false negatives do skin test,al ergic reaction caused by the incidence of 7%;Concentration to 1250 ug/ml skin test in 9 cases of false negative results,caused by an al ergic reaction rate was 4.5%.Comparing the two X squared=1.15,>0.05).Conclusion Try not prove that improve ceftriaxone sodium sensitive liquid concentration can reduce the incidence of skin test false negative results caused by an al ergic reaction.