替米沙坦与吲哒帕胺对正常高值血压糖脂代谢的影响

Effects of Telmisartan and Indapamide on Glucose and Lipid Metabolism in High Normal Blood Pressure

目的:分析替米沙坦与吲哒帕胺对正常高值血压糖脂代谢的影响。方法选取我院2011年11月~2012年10月收治的正常高值血压患者162例,将其随机分为观察组和对照组各81例,观察组给予服用替米沙坦,对照组服用吲哒帕胺,比较两组患者用药后血压及血糖、血脂等生化指标变化情况。结果观察组用药后收缩压、舒张压分别为(125.84±3.02)mmHg、(76.83±4.55)mmHg,与对照组比较无明显差异,>0.05;而TC、TG、HDL-C均高于对照组,两组比较差异显著,差异具有统计学意义,<0.01;且LDL-C显著低于对照组,两组对比差异明显,<0.01;而观察组患者FPG与对照组无统计学差异,>0.05。结论正常高值血压患者服用替米沙坦和吲哒帕胺均可有效降低血压,而替米沙坦可改善患者糖脂代谢,可作为高血压的预防药物在临床应用。

Objective To analyze the telmisartan and YinDaPaAn glucolipid metabolism of blood pressure on the normal high values.Methods From November 2011 to October 2011 treated 162 patients with normal blood pressure high value,its each 81 cases were randomly divided into observation group and control group,observation group was given taking telmisartan,take YinDaPaAn control group,compared two groups of patients after blood pressure and blood sugar,blood lipids and other biochemical index changes.Results Observation group after systolic pressure,diastolic pressure(125.84+/-3.02 mmHg,respectively(76.83+4.55)mmHg,compared with the control group no significant dif erence,P>0.05;While the TC,TG,HDL-C were higher than control group,two groups is significant dif erence,the dif erence is statistically significant,<0.01;And LDL-C was significantly lower than the control group,significant dif erence comparing the two groups,<0.01;And the observation group of patients with FPG no statistical dif erence with control group,>0.05).Conclusion High normal values of blood pressure in patients with telmisartan and YinDaPaAn al can ef ectively reduce the blood pressure,and telmisartan glucolipid metabolism,can improve patients can be used as the prevention of high blood pressure drugs in clinical application.