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OCT4在食管鳞癌中的表达及意义

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摘要 目的探讨在食管鳞癌中八聚体4(octamer 4,OCT4)的表达及其意义。方法检测60例食管鳞状细胞癌和20例食管正常组织OCT4的表达,并与食管癌病理特征关系进行探讨。结果 OCT4在食管鳞癌组织和正常上皮组织中的阳性表达率分别为71.7%和20%(<0.01),差异有统计学意义。OCT4的表达与食管鳞癌组织中癌细胞的浸润深度和淋巴结转移呈正相关(<0.05)。结论在食管癌组织中OCT4的表达异常增高,提示其与食管癌的发生、发展有密切的关系。
出处 《医学信息(医学与计算机应用)》 2014年第20期231-232,233,共3页 Medical Information
基金 皖南医学院中青年科学基金(WK200906F)。
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