妊娠期妇女血清总胆汁酸检测的意义

Pregnant Women Serum Total Bile Acid Detection Significance

目的:探讨妊娠期孕妇血清总胆汁酸(TBA)在妊娠过程中的变化。方法选取2013年3月~2014年3月本院收治的120例孕妇(其中孕早期、孕中期、孕晚期妇女各40例)为观察组,30例来本院健康体检的妇女为对照组,采用酶法定量检测两组总胆汁酸含量。结果对照组和观察组(孕早期、孕中期、孕晚期)总胆汁酸含量分别为(1.25±0.43)umol/L和(2.18±1.01)umol/L、(3.46±1.24)umol/L、(6.26±4.35)umol/L;观察组孕妇血清中TBA水平均高于对照组。结论总胆汁酸含量持续升高对孕妇和胎儿都会造成很大危害,因此血清总胆汁酸的测定具有重要意义。

Objective Explore pregnancy pregnant women serum total bile acid in the change in the process of pregnancy.Methods Selection in March 2013 to March 2014 in our hospital treated 120 cases of pregnant women(pregnant early,mid pregnancy and late pregnancy women 40 cases)as the observation group,30 patients to our hospital physical examination of women as the control group,using enzymatic quantitative detection of two groups of total bile acid content.Results Control group and observation group(pregnancy early and mid pregnancy and late pregnancy)total bile acid content(1.25+0.43)respectively umol/L and(2.18+1.01)umol/L,(3.46±1.24)umol/L,(6.26±4.35)umol/L;Pregnant women serum levels of associates observation group were higher than the control group.Conclusion Total bile acid levels continue to rise for pregnant women and fetus can cause great harm,so the determination of serum total bile acid is of great significance.