丙泊酚在体外循环手术中的稳定血压作用

Stable Blood Pressure Effects of Propofol During Cardiopulmonary Bypass in the Operation

目的:探讨体外循环手术中使用丙泊酚对血流动力学稳定的作用。方法对43例行体外循环下心脏直视手术患者随机分为治疗组和对照组,其中治疗组22例在心脏体外循环手术中使用丙泊酚加硝酸甘油稳定血压,对照组21例单纯使用硝酸甘油控制血压,监测两组患者体外循环手术期间的有创血压,计算血压变异性。结果治疗组在体外循环手术期间的血压变异性明显低于对照组。结论丙泊酚适合在体外循环心脏直视手术中使用,对手术应激反应有抑制作用,可以维持血流动力学稳定,血压波动更小,对于患者安全渡过手术麻醉期有极大临床价值。

Objective To explore the effect of propofol on hemodynamic stability used in extracorporeal.Methods In 43 patients under cardiopulmonary bypass in patients undergoing open heart operation were randomly divided into treatment group and control group.22 cases in treatment group in cardiopulmonary bypass operation using propofol plus nitroglycerin stable blood pressure,21 cases in the control group only using nitric acid.Results The treatment group during extracorporeal circulation operation on blood pressure variability was significantly lower than the control group.Conclusion Propofol is suitable for use in open heart operation with extracorporeal circulation,inhibit stress response in the operation,can maintain the stability of hemodynamics,blood pressure fluctuations smaller,has great clinical value for patient safety through operation anesthesia.