2Ishibashi T, Pitcairn GR, Yoshino H, et al. Scintigraphic evaluation of a new capsule-type colon specific drug delivery system in healthy volunteers [J]. J Pharm Sci, 1998, 87(5) : 531-537
3Sinha V R, Kumria R. Microbially triggered drug delivery to the colon [J]. Eur J Pharm Sci, 2003, 18(1):3-18
4Metcalf AM, Phillips SF, Zinsmeister AR, et al. Simplified assessment of segmental colonic transit[J]. Gastroenterology, 1987,29:40-47
5Van den Mooter G, Samyn C, Kinget R. Azo polymers for colon-specific drug delivery[J]. Int J Pharm, 1992, 87:37-46
6Saffran M, Kumar GS, Savariar C, et al. A new approach to the oral administration of insulin and other peptides drugs[J]. Science, 1986, 233:1081-1084
7Van den Mooter G, Samyn C. Kinget R. The relation between swelling properties and enzymatic degradation of azo polymers designed for colon-spcific drug delivery[J]. Pharm Res, 1994, 11(12):1737-1741
8Sinha V R, Kumria R. Polysaceharides in colon-specific drug delivery [J].Int J Pharm, 2001, 224(1-2): 19-38
9Muraokea M, Hu Z, Shimokawa T, et al. Evaluation of intestinal pressurecontrolled colon delivery capsule containing caffeine as a model drug in human volunteers[J]. J Control Release, 1998,52(1/2):119-129
10Masataka K, Shunsuke W, Hitoshi K, et al. Studies on lactulose formulations for colon-specific drug delivery[J].Int J Pharm, 2002, 249:33-43
