新生儿生理性黄疸早期主动药物干预研究

Neonatal Physiological Jaundice Early Active Drug Intervention Study

目的了解新生儿生理性黄疸早期主动药物干预效果。方法选取2012年1月~2014年4月在我院产科出生的500例发生生理性黄疸足月新生儿为研究对象,随机分为观察组和对照组各250例。对照组只给予早期少量多次喂温水和尽早开奶措施,观察组在对照组的基础上采取早期主动药物(茵桅黄口服液+酷酸梭菌活菌散剂)干预措施,两组采用JH20-1B黄疸仪测定1次/d,比较两组效果和黄疸高峰持续时间。结果对照组干预有效率为72.4%,观察组干预有效率为97.6%,两组对比差异性显著,有统计学意义(<0.05)。观察组黄疸高峰期持续时间明显短于对照组,两组对比差异性显著,有统计学意义(<0.05)。结论新生儿生理性黄疸早期主动药物干预安全、有效、值得临床推广应用。

Objective To understand the neonatal physiological jaundice early active drug intervention ef ect.Methods Selectioned January 2012~April 2014 was born in February of 500 cases of physiological jaundice ful-term newborns as the research object,were randomly divided into observation group and control group 250 cases each.Control group given early a few times to feed water and milk measures as soon as possible,on the basis of the observation group in the control group take early active drugs(Yin mast yel ow oral liquid+cool living bacterium acid bacteria powder)intervention measures,two groups of daily use JH20-1 b jaundice meter measuring,comparing two groups of ef ect and duration of jaundice peak.Results The ef ective rate was 72.4%,control group intervention group intervention ef ective rate was 97.6%,the boundary of comparing the two groups have statistical significance(<0.05).Jaundice peak duration of observation group was obviously shorter than the control group,the boundary of comparing the two groups have statistical significance(<0.05).Conclusion Neonatal physiological jaundice early active drug intervention safe,ef ective and worth clinical application.