重组人干扰素a-1b治疗小儿上呼吸道感染75例疗效观察

Clinical Observation of 75 Cases of Recombinant Human Interferon a-1b Treatment in Children with Upper Respiratory Tract Infection

儿科临床中我们常见的感染症状基本都是病毒引起的,但是现在我们还没有研制出非常有效的抗病毒药物。干扰素的问世填补了这一项的空白,干扰素被证实具有广谱抗病毒、抗肿瘤和免疫调节作作用。重组人干扰素a-1b是一种采用健康人白细胞来源的干扰素基因克隆和表达的基因工程干扰素,由于其疗效显著、副作用低、不易产生中和抗体等优点,近年来已逐渐在临床上得到了应用。目前我国严格控制使用抗生素,病毒性感染疾病使用干扰素,可以减少滥用抗生素,在儿科有广泛的应用。本文主要综述干扰素在儿科常见几种病中的应用。

Is caused by a virus infection symptoms we arecommon clinical pediatrics,but now we have not yet developed a very ef ective antiviral drug.Interferon hasfil ed the blank of this item,interferon was confirmed with broad-spectrum anti-virus,anti-tumor and immune regulation function.Recombinant human interferon a-1b isgenetic engineering interferon and an expression of thehealthy human leukocyte derived interferon gene cloning,because of its remarkable curative ef ect,low side ef ect,not easy to produce such antibodies to neutralize theadvantages,in recent years it has gradual y been appliedin clinical.At present,strictly control the use of antibiotics,viral infection,the use of interferon,can reduce the abuse of antibiotics,is widely used in pediatrics.This article reviews the application of interferon in several common disease in pediatrics.