美托洛尔治疗COPD合并急性冠脉综合征疗效观察

Efficacy of COPD Patients with Acute Coronary Syndrome Metoprolol

目的:探讨美托洛尔治疗慢性阻塞性肺病(COPD)合并急性冠脉综合征(aACS)的疗效观察。方法将60例COPD合并ACS患者分为观察组和对照组各30例。对照组采用常规治疗方法,不应用任何β-受体拮抗剂,观察组在常规治疗基础上使用美托洛尔治疗。评价两组治疗前后血压、心率、存活率、肺功能情况,以判断美托洛尔的治疗效果和不良反应。结果观察组患者2个月后心率、收缩压、舒张压较治疗前有显著差异(P<0.05)。生存率与对照组比较有统计学差异(P<0.05)。两组在对肺功能的影响上无统计学意义(P>0.05)。结论美托洛尔治疗COPD合并ACS有很好的治疗效果,而且对肺功能无影响,是临床中值得运用的可靠选择。

Objective To investigate the metoprolol treatment of chronic obstructive pulmonary disease(COPD)patients with acute coronary syndrome ef icacy(aACS)'s.Methods 60 COPD patients with ACS were divided into observation group and control group of 30 cases.Control group using conventional treatment methods,without applying anyβ-receptor antagonists,metoprolol treatment group was observed in conventional therapy.Evaluation of blood pressure,heart rate,survival rate,lung function before and after treatment of the two groups to determine the therapeutic ef ects of metoprolol and adverse reactions.Results The patients two months after the heart rate,systolic blood pressure,a significant dif erence(P<0.05)compared with pre-treatment diastolic blood pressure.There were significant dif erences(P<0.05)survival rate of the control group.2 groups on the impact on lung function was not statistical y significant(>0.05).Conclusion COPD with metoprolol ACS has a good therapeutic ef ect,but had no ef ect on lung function,is worthy of clinical use and reliable choice.