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原发性高血压合并糖耐量减低患者血清hs-CRP水平变化及意义

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摘要 目的探讨在原发性高血压合并糖耐量减低(IGT)患者中,高敏C-反应蛋白(hs-CRP)水平的变化及其意义。方法入选2013年2月~2014年1月门诊、病房高血压患者及健康体检人群,分为病例组(n=55)与对照组(n=25),其中病例组根据口服糖耐量试验(OGTT)2h血糖分为单纯高血压组及高血压合并糖耐量减低(IGT)组,所有入选者检测空腹血糖、OGTT 2h血糖、hs-CRP。结果高血压组hs-CRP水平高于对照组(﹤0.05);高血压合并IGT组hs-CRP水平显著高于对照组(﹤0.001);两病例组比较,高血压合并IGT组hs-CRP水平高于高血压组(﹤0.05);高血压合并IGT组OGTT 2h 血糖与hs-CRP水平呈正相关(r=0.477,=0.012)。结论高血压患者体内hs-CRP水平升高,且合并IGT后会出现更高的hs-CRP水平,hs-CRP激活可能在高血压及糖耐量减低发病过程中起重要作用。
作者 王胜利
出处 《医学信息(医学与计算机应用)》 2014年第13期458-458,共1页 Medical Information
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